Progress in Pharmacodynamics and Experimental Therapeutics

The neurochemistry of therapeutics: levodopa pharmacodynamics in Parkinson's disease.

Parkinson’s disease (PD), the most common neurodegenerative movement disorder, has enjoyed a recent explosion of treatment options available for its symptomatic management. Despite these recent introductions, PD remains a progressive disorder, with the majority of patients experiencing significant disability in its more advanced stages. One aspect of PD leading to disability is the development ...

Bioconjugate Therapeutics: Current Progress and Future Perspective.

Multifunctional nanoparticles: recent progress in cancer therapeutics.

Although much progress has been made in treating cancers, cancer death rates in and around the United States are still high. Current treatments are either ineffective against some cancers or detrimental to patients, which decreases their quality of life. The use of nanotechnology in cancer therapy can potentially increase patient survival, reduce side effects, and reduce mortality rates because...

hydrochlorothiazide detection in urine samples by hplc-dad and experimental design dispersive l-l microextraction

hydrochlorothiazide (hct) is a diuretic agent which is shown to be effective in the treatment of hypertension. literature reports have demonstrated that urinary excretion data may be used to assess the bioavailability of various formulations containing this thiazide. also hct consumption by the athletes is one of the drugs which should be regulated by world anti-doping agency (wada), because of...

simulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water

abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...